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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1075 | Vitamin K1 | Phylloquinone,Phytomenadione,Phytonadione,Phyllohydroquinone | Others , Endogenous Metabolite |
Vitamin K1 (Phylloquinone) a fat-soluble, naturally occurring vitamin with antihemorrhagic and prothrombogenic activity. | |||
T36730 | Vitamin K1 2,3-epoxide | Vitamin K1 epoxide,Phylloquinone oxide,Vitamin K1 2,3-epoxide | Others |
Vitamin K1 2,3-epoxide (Phylloquinone oxide) is reduced to vitamin k and is involved in the vitamin k cycle. | |||
T7636 | Phenprocoumon | ||
Phenprocoumon is an antagonist of vitamin K(IC50:1 μM). | |||
T0809 | Dicoumarol | Dicumarol | Dehydrogenase , NADPH , PDK |
Dicoumarol (Dicumarol) is a hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicoumarol is a competitive inhibitor of vitamin K epoxidereductase; t... | |||
T17025 | Tecarfarin | ATI-5000,ATI-5923 | Others |
Tecarfarin (ATI-5923) is an orally active and potent vitamin K epoxide reductase (VKOR) antagonist and cannabinoid-1 receptor inverse agonist with antithrombotic activity that attenuates abdominal pain and increases inte... | |||
T4980 | Betrixaban maleate | Factor Xa | |
Betrixaban maleate is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa. | |||
T4341 | Betrixaban | PRT054021 | Factor Xa |
Betrixaban (PRT054021) is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa [1]. It was selected among all lead compounds due to its low hERG channel ... | |||
T75435 | Cis-Vitamin K1 | ||
Cis-Vitamin K1 is an endogenous metabolite of Vitamin K [1] . | |||
TP1628 | Activated Protein C (390-404), human | ||
Activated Protein C (390-404), human, a peptide derived from the vitamin K-dependent serine protease, effectively suppresses the anticoagulant activity of APC[1]. | |||
T81205 | SARS-CoV-2-IN-66 | SARS-CoV | |
SARS-CoV-2-IN-66 (1), a derivative of vitamin K, functions as an inhibitor of SARS-CoV-2, exhibiting an effective concentration (EC50) of 70.8 μM in VeroE6/TMPRSS2 cells [1]. | |||
T81204 | SARS-CoV-2-IN-67 | SARS-CoV | |
SARS-CoV-2-IN-67 (Compound 16), a derivative of vitamin K, exhibits anti-SARS-CoV-2 properties, with an effective concentration (EC50) of 64.8 μM in VeroE6/TMPRSS2 cells, and inhibits SARS-CoV-2 RdRp activity [1]. | |||
T37950 | 2-(Isopentylamino)naphthalene-1,4-dione | ||
2-(Isopentylamino)naphthalene-1,4-dione is a vitamin K analog.1It inhibits spasms induced by pentylenetetrazole and tonic hindlimb extension induced by maximal electroshock (MES) in mice (ED50s = 349.2 and 108.1 mg/kg, r... | |||
T21693 | PPM-18 | ||
PPM-18 (NSC 73233) is a potent anti-inflammatory agent which inhibits nitric oxide synthase expression. PPM-18 is a potent inhibitor of iNOS expression by blocking the binding of NF-κB to promoter [1]. PPM-18 is an analo... |